Well it has been 22 days since I started trt. I haven't really noticed much difference as yet. but i am told by my doctor and others that the real difference won't be noticed for about three months. the only thing I have noticed at this point is more morning wood and my testicles are smaller. They have seemed to have slowed down shrinking at this point, with the left ball about half the size it was and the right about a quarter smaller.